AJOVY Dosing Instructions

Welcome. This guide will help you self-administer AJOVY for migraine prevention. [warmly] Depending on your prescription, you will either give yourself one injection monthly... or three separate injections once every three months. First, verify your dose and gather your supplies: your AJOVY autoinjector, alcohol swabs, cotton balls, and a sharps disposal container. [serious] Do not shake the device. Remove the autoinjector from the refrigerator and let it sit in the carton at room temperature for 30 minutes. [beat] This makes the injection more comfortable. Never use a microwave or hot water to warm it. Wash your hands thoroughly with soap and water. Inspect the device window. The liquid should be clear. If you see air bubbles—[reassuring]—that is normal. Do not try to remove them. Now, choose your injection site: the stomach avoiding the belly button, the front of the thighs, or the fleshy back of the upper arms. Clean the area with a new alcohol swab and let it air dry completely. When you are ready, pull the protective cap straight off. [emphasized] Do not twist it... and never put the cap back on. Place the autoinjector at a 90-degree angle against your skin. Press down firmly—and hold. You will hear a distinct click. [click] This means the injection has started. Keep holding it down. [pause] About 15 seconds later, you will hear a second click. [click] [slows down] Do not lift yet. Wait another 10 seconds to ensure the full dose is delivered. Check that the blue plunger fills the window... then lift the device straight up. Press a cotton ball gently on the site. Do not rub the area. Dispose of the used autoinjector immediately in your sharps container. If you have the quarterly dose, repeat these steps with your remaining pens in different spots. You have successfully administered AJOVY.

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